Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22093206 | 0.86 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL24102626 | 0.82 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL1396117 | 0.76 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL13560597 | 0.76 | CPB2 (0.37) | DGAT1 | |
| SCHEMBL22093251 | 0.75 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL2822834 | 0.74 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL27089125 | 0.74 | — | — | |
| SCHEMBL25130068 | 0.74 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL24102560 | 0.74 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL22093263 | 0.74 | CPB1 (0.33) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165035-A1 | HETEROARYL ALKYLENE SUBSTITUTED 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | Ideaya Biosciences, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |
| WO-2021252678-A1 | HETEROARYL ALKYLENE SUBSTITUTED 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2021-12-16 | — | — | WO | disclosed |