Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.35 |
| ▸ | TTR | P02766 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | EYA2 | O00167 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26211957 | 0.94 | EYA3 (0.42) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL24102960 | 0.93 | EYA3 (0.42) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL22072522 | 0.85 | EYA3 (0.45) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL22680471 | 0.81 | EYA3 (0.54) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL20718288 | 0.80 | EYA3 (0.55) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL20718309 | 0.78 | EYA3 (0.44) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL20718353 | 0.77 | EYA3 (0.43) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL20718531 | 0.76 | EYA3 (0.51) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL24267018 | 0.76 | EYA3 (0.36) | EYA3CYP2C19SLC22A12TTR | |
| SCHEMBL24267020 | 0.74 | EYA3 (0.35) | EYA3SLC22A12TTRPTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252630-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ARTHROSI THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |