Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.37 |
| ▸ | TTR | P02766 | 4/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | EYA2 | O00167 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26211957 | 0.91 | EYA3 (0.42) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL24267018 | 0.90 | EYA3 (0.36) | EYA3CYP2C19SLC22A12TTR | |
| SCHEMBL22072500 | 0.86 | EYA3 (0.58) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL24103744 | 0.85 | EYA3 (0.42) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL24102960 | 0.85 | EYA3 (0.42) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL24267020 | 0.79 | EYA3 (0.35) | EYA3SLC22A12TTRPTPN1PTPN2 | |
| SCHEMBL24266787 | 0.79 | EYA3 (0.36) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL25815018 | 0.77 | EYA3 (0.77) | EYA3CYP2C19SLC22A12TTRPTPN1 | |
| SCHEMBL26211199 | 0.76 | CYP2C19 (0.41) | EYA3CYP2C19SLC22A12TTRALDH1A1 | |
| SCHEMBL25719657 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957629-B1 | PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF | ARTHROSI THERAPEUTICS INC (US) | 2023-09-06 | — | — | EP | disclosed |
| WO-2023098872-A1 | CRYSTALLINE FORMS OF A COMPOUND FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| WO-2020118114-A1 | METHODS FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020118113-A1 | CRYSTALLINE FORMS OF A COMPOUND FOR TREATING OR PREVENTING GOUT OR HYPERURICEMIA | ARTHROSI THERAPEUTICS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |