Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 3/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22072522 | 0.90 | EYA3 (0.45) | EYA3SLC22A12TTRCYP2C19 | |
| SCHEMBL24267020 | 0.90 | EYA3 (0.35) | EYA3SLC22A12TTR | |
| SCHEMBL26211957 | 0.82 | EYA3 (0.42) | EYA3SLC22A12TTRCYP2C19 | |
| SCHEMBL24266787 | 0.77 | EYA3 (0.36) | EYA3SLC22A12TTRCYP2C19 | |
| SCHEMBL22072500 | 0.77 | EYA3 (0.58) | EYA3SLC22A12TTRCYP2C19 | |
| SCHEMBL24102960 | 0.76 | EYA3 (0.42) | EYA3SLC22A12TTRCYP2C19 | |
| SCHEMBL24103744 | 0.76 | EYA3 (0.42) | EYA3SLC22A12TTRCYP2C19 | |
| SCHEMBL26212284 | 0.75 | TTR (0.47) | EYA3SLC22A12TTRCYP2C19 | |
| SCHEMBL26211199 | 0.74 | CYP2C19 (0.41) | EYA3SLC22A12TTRCYP2C19 | |
| SCHEMBL25719657 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957629-B1 | PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF | ARTHROSI THERAPEUTICS INC (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-3957629-A1 | PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF | Arthrosi Therapeutics, Inc. (US) | 2022-02-23 | — | — | EP | disclosed |