Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 8/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 8/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 8/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 8/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110120 | 0.82 | KDM4E (0.35) | ALDH1A1KDM4EPKMHDAC1HDAC6 | |
| SCHEMBL25800557 | 0.82 | HSP90AA1 (0.42) | ALDH1A1KDM4EPKMHDAC1HDAC6 | |
| SCHEMBL24109953 | 0.80 | EPAS1 (0.36) | ALDH1A1KDM4EPKMABCC9ABCC8 | |
| SCHEMBL24110121 | 0.79 | CYP11B2 (0.36) | ALDH1A1KDM4EPKM | |
| SCHEMBL30449524 | 0.74 | OPRM1 (0.38) | ALDH1A1KDM4EPKMABCC9ABCC8 | |
| SCHEMBL24110168 | 0.74 | OPRM1 (0.38) | ALDH1A1KDM4EPKMABCC9ABCC8 | |
| SCHEMBL24109659 | 0.72 | ATM (0.39) | ALDH1A1KDM4EPKMCSNK2A1SCARB1 | |
| SCHEMBL24109528 | 0.71 | FADS1 (0.36) | ALDH1A1KDM4EPKM | |
| SCHEMBL24110170 | 0.70 | GRM5 (0.37) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL30448814 | 0.70 | GRM5 (0.37) | ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219890-A1 | BICYCLIC COMPOUNDS AND USE THEREOF | BETTA PHARMACEUTICALS CO LTD (CN) | 2023-07-13 | — | — | US | disclosed |
| US-20230219890-A1 | BICYCLIC COMPOUNDS AND USE THEREOF | BETTA PHARMACEUTICALS CO LTD (CN) | 2023-07-13 | — | — | US | disclosed |
| WO-2021249463-A1 | BICYCLIC COMPOUND AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2021-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219890-A1 | BICYCLIC COMPOUNDS AND USE THEREOF | CYP11B2, CYP11B1, CYP1B1 | ALDH1A1 445/4885KDM4E 3088/4885PKM 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.