Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | POLG | P54098 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 3/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28087780 | 0.92 | KDM4E (0.37) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL18486650 | 0.84 | PNP (0.39) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL18486711 | 0.83 | KDM4E (0.38) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| Pterine SCHEMBL27777837 | 0.77 | POLB (0.47) | POLBPNPPOLGAKR1B1POLA1 | |
| Phosphoric Acid SCHEMBL29043332 | 0.75 | GAA (0.39) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL27483301 | 0.75 | KDM4E (0.38) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3639474 | 0.75 | KDM4C (0.48) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28478046 | 0.73 | KDM4E (0.43) | KDM4EGAAALDH1A1SMN1; SMN2HPGD | |
| Triphosphate SCHEMBL28078341 | 0.72 | POLG (0.52) | POLBPNPPOLGAKR1B1POLA1 | |
| SCHEMBL9444229 | 0.72 | KDM4E (0.40) | KDM4EGAAALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2538931-B1 | PRODUCTS AND METHODS | UNIV DURHAM (GB) | 2016-08-03 | — | — | EP | disclosed |
| US-20130039856-A1 | Products and Methods | UNIVERSITY OF DURHAM (GB) | 2013-02-14 | — | — | US | disclosed |
| EP-2538931-A1 | PRODUCTS AND METHODS | University Of Durham (GB) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011104515-A1 | PRODUCTS AND METHODS | UNIVERSITY OF DURHAM (GB) | 2011-09-01 | — | — | WO | disclosed |