Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19605969 | 0.88 | CTSB (0.38) | CTSLCTSBCTSS | |
| SCHEMBL23506393 | 0.80 | CTSL (0.39) | CTSLCTSBCTSS | |
| SCHEMBL21702165 | 0.77 | CTSL (0.38) | CTSLCTSB | |
| SCHEMBL19606056 | 0.75 | CTSB (0.39) | CTSLCTSBCTSS | |
| SCHEMBL24113343 | 0.74 | CTSB (0.38) | CTSLCTSBCTSS | |
| SCHEMBL24690561 | 0.74 | — | — | |
| SCHEMBL22758564 | 0.73 | — | — | |
| SCHEMBL24113138 | 0.72 | CTSB (0.40) | CTSLCTSBCTSS | |
| SCHEMBL25249170 | 0.72 | CTSB (0.40) | CTSLCTSBCTSS | |
| SCHEMBL29062993 | 0.72 | CTSB (0.40) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |