Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24115513 | 0.94 | UTS2R (0.38) | UTS2RHRH3ADRB2ADRB1ADRB3 | |
| SCHEMBL24115510 | 0.84 | MMP1 (0.39) | KMT2AMEN1KDM4EMAPTPOLB | |
| SCHEMBL24115523 | 0.83 | UTS2R (0.39) | UTS2RHRH3ADRB2ADRB1ADRB3 | |
| SCHEMBL24115475 | 0.79 | HTR2A (0.42) | ADRB2HTR2AHTR2CHTR2B | |
| SCHEMBL21443074 | 0.78 | CYP1A2 (0.48) | UTS2RKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL569280 | 0.75 | TDP1 (0.44) | HRH3ADRB1KMT2AMEN1DRD3 | |
| SCHEMBL22767881 | 0.75 | PIN1 (0.49) | UTS2RHRH3CTSBCTSSCTSK | |
| SCHEMBL24115516 | 0.74 | HTR2A (0.40) | ADRB2HTR2AHTR2CHTR2B | |
| SCHEMBL16113819 | 0.72 | MEN1 (0.40) | CTSBCTSSKMT2AMEN1MAPT | |
| SCHEMBL25977545 | 0.71 | MEN1 (0.41) | ADRB2ADRB1ADRB3CTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11203565-B2 | Ester compound and PIN1 inhibitor, inflammatory disease therapeutic, and colon cancer therapeutic in which said ester compound is used | HIROSHIMA UNIVERSITY (JP) | 2021-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11203565-B2 | Ester compound and PIN1 inhibitor, inflammatory disease therapeutic, and colon cancer therapeutic in which said ester compound is used | PIN1, APC, GSKIP | UTS2R 4200/4885HRH3 4245/4885ADRB2 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.