Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694096 | 0.84 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9ATDP1LMNA | |
| SCHEMBL7698454 | 0.83 | NQO2 (0.45) | SMN1; SMN2NPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL7697161 | 0.81 | MAOA (0.43) | RAB9AL3MBTL1MAOAMAOBNQO2 | |
| SCHEMBL7697050 | 0.81 | TDP1 (0.44) | L3MBTL1TDP1MAOAMAOBDHFR | |
| SCHEMBL7699341 | 0.77 | LMNA (0.45) | SMN1; SMN2NPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL7692496 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1TDP1LMNAMEN1 | |
| SCHEMBL7695424 | 0.75 | CYP1A2 (0.42) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL7695589 | 0.75 | APP (0.46) | SMN1; SMN2NPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL24115709 | 0.75 | NQO2 (0.49) | SMN1; SMN2NPC1RAB9AL3MBTL1TDP1 | |
| SCHEMBL7697719 | 0.74 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |