Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342230 | 0.90 | MAPT (0.37) | MAPTALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL22342229 | 0.87 | ALDH1A1 (0.55) | MAPTALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL20734754 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL2491027 | 0.77 | KDM4E (0.53) | MAPTALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL16644141 | 0.77 | NQO2 (0.53) | MAPTALDH1A1POLBKDM4ENQO2 | |
| Ammonia Solution, Strong SCHEMBL28585108 | 0.75 | KDM4E (0.52) | MAPTALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL24115709 | 0.74 | NQO2 (0.49) | MAPTALDH1A1MAPK1POLBKDM4E | |
| Hydrochloric Acid SCHEMBL28608867 | 0.73 | KDM4E (0.50) | MAPTALDH1A1MAPK1POLBKDM4E | |
| SCHEMBL18866930 | 0.73 | NPC1 (0.39) | MAPTALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL16643873 | 0.73 | MEN1 (0.36) | MAPTALDH1A1MAPK1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045090-A1 | BISPECIFIC ANTIBODIES | IMMUNOMAB, INC. (US) | 2018-03-08 | — | — | WO | disclosed |