Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | GJB2 | P29033 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | GJA1 | P17302 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21013401 | 0.91 | HTR1A (0.49) | BCHETACR2HTR1ANT5EACHE | |
| SCHEMBL16632221 | 0.91 | HTR1A (0.49) | BCHETACR2HTR1ANT5EACHE | |
| SCHEMBL16632218 | 0.91 | HTR1A (0.49) | BCHETACR2HTR1ANT5EACHE | |
| SCHEMBL1033003 | 0.91 | HTR1A (0.49) | BCHETACR2HTR1ANT5EACHE | |
| SCHEMBL8733842 | 0.91 | HTR1A (0.49) | BCHETACR2HTR1ANT5EACHE | |
| SCHEMBL13164470 | 0.91 | HTR1A (0.49) | BCHETACR2HTR1ANT5EACHE | |
| SCHEMBL1033002 | 0.91 | HTR1A (0.49) | BCHETACR2HTR1ANT5EACHE | |
| SCHEMBL16229071 | 0.91 | HTR1A (0.49) | BCHETACR2HTR1ANT5EACHE | |
| SCHEMBL8708672 | 0.85 | GJB2 (0.52) | GJB2TACR2HTR1ANT5EGJA1 | |
| SCHEMBL26989684 | 0.85 | GJB2 (0.47) | BCHEGJB2TACR2HTR1ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287028-A1 | C-MANNOSIDE COMPOUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-09-14 | — | — | US | disclosed |
| US-11697665-B2 | C-mannoside compounds useful for the treatment of urinary tract infections | FIMBRION THERAPEUTICS, INC. (US) | 2023-07-11 | — | — | US | disclosed |
| US-20210395287-A1 | C-MANNOSIDE COMPOUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395287-A1 | C-MANNOSIDE COMPOUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS | MANBA, MAN2B2, FUCA1 | BCHE 597/4885GJB2 4777/4885TACR2 2431/4885 |
| US-11697665-B2 | C-mannoside compounds useful for the treatment of urinary tract infections | MANBA, MAN2B2, FUCA1 | BCHE 597/4885GJB2 4777/4885TACR2 2431/4885 |
| US-20230287028-A1 | C-MANNOSIDE COMPOUNDS USEFUL FOR THE TREATMENT OF URINARY TRACT INFECTIONS | MANBA, MAN2B2, FUCA1 | BCHE 597/4885GJB2 4777/4885TACR2 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.