Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3866729 | 0.91 | ITGAL (0.51) | ITGALROCK2ROCK1ITGB1ITGA5 | |
| SCHEMBL16286432 | 0.91 | ITGAL (0.51) | ITGALROCK2ROCK1ITGB1ITGA5 | |
| SCHEMBL30227636 | 0.91 | ITGAL (0.51) | ITGALROCK2ROCK1ITGB1ITGA5 | |
| SCHEMBL3871439 | 0.89 | ITGAL (0.51) | ITGALROCK2ROCK1ITGB1ITGA5 | |
| SCHEMBL21939751 | 0.85 | ITGAL (0.42) | ITGALROCK2ROCK1ITGB1ITGA5 | |
| SCHEMBL3866036 | 0.85 | ITGAL (0.46) | ITGALROCK2ROCK1ITGB1ITGA5 | |
| SCHEMBL3866964 | 0.84 | ITGAL (0.49) | ITGALITGB1ITGA5NPC1RAB9A | |
| SCHEMBL3869362 | 0.84 | ITGAL (0.49) | ITGALROCK2ROCK1ITGB1ITGA5 | |
| SCHEMBL3867450 | 0.83 | ITGAL (0.45) | ITGALROCK2ROCK1ITGB1ITGA5 | |
| SCHEMBL3876678 | 0.83 | ITGAL (0.48) | ITGALROCK2ROCK1ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210393811-A1 | Imaging Agents and Methods of Use | TEXAS HEART INSTITUTE | 2021-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210393811-A1 | Imaging Agents and Methods of Use | ITGA1, ITGA4, CD47 | ITGAL 15/4885ROCK2 4295/4885ROCK1 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.