Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24119238 | 0.92 | ITGB3 (0.35) | ITGALITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL21939750 | 0.92 | ITGB3 (0.44) | ITGALITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL24119321 | 0.85 | ITGAL (0.46) | ITGALITGB1ITGA5NPC1RAB9A | |
| SCHEMBL24119303 | 0.85 | FOLH1 (0.39) | ITGALITGB1ITGA5 | |
| SCHEMBL30227636 | 0.85 | ITGAL (0.51) | ITGALITGB1ITGA5NPC1RAB9A | |
| SCHEMBL3866729 | 0.85 | ITGAL (0.51) | ITGALITGB1ITGA5NPC1RAB9A | |
| SCHEMBL16286432 | 0.85 | ITGAL (0.51) | ITGALITGB1ITGA5NPC1RAB9A | |
| SCHEMBL24119272 | 0.85 | MMP13 (0.38) | ITGB3ITGA2BITGB1ITGA5NPC1 | |
| SCHEMBL24119278 | 0.83 | ITGB1 (0.45) | ITGALITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL3871439 | 0.83 | ITGAL (0.51) | ITGALITGB1ITGA5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210393811-A1 | Imaging Agents and Methods of Use | TEXAS HEART INSTITUTE | 2021-12-23 | — | — | US | disclosed |
| WO-2020072784-A1 | IMAGING AGENTS AND METHODS OF USE | TEXAS HEART INSTITUTE (US) | 2020-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210393811-A1 | Imaging Agents and Methods of Use | ITGA1, ITGA4, CD47 | ITGAL 15/4885ITGB3 12/4885ITGA2B 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.