Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923971 | 0.86 | RORC (0.47) | HRH3HTR2AHTR2CACACBRORC | |
| SCHEMBL16451234 | 0.82 | HRH3 (0.47) | HRH3L3MBTL1MEN1KMT2AHTR2A | |
| SCHEMBL189433 | 0.81 | MAPT (0.47) | HRH3L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL24123779 | 0.79 | ADRB1 (0.44) | HRH3L3MBTL1NOTUMMEN1KMT2A | |
| SCHEMBL26498514 | 0.78 | L3MBTL1 (0.41) | HRH3L3MBTL1NOTUMMEN1KMT2A | |
| SCHEMBL12499527 | 0.77 | HRH3 (0.37) | HRH3MGLLHTR2AHTR2CRORC | |
| SCHEMBL24352426 | 0.77 | L3MBTL1 (0.43) | HRH3L3MBTL1NOTUMMEN1KMT2A | |
| SCHEMBL22854281 | 0.77 | L3MBTL1 (0.43) | HRH3L3MBTL1NOTUMMEN1KMT2A | |
| SCHEMBL30206343 | 0.77 | MCHR1 (0.37) | HRH3HTR2AHTR2C | |
| SCHEMBL30493024 | 0.76 | DDB1 (0.49) | HRH3NOTUMMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021254389-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2021-12-23 | — | — | WO | disclosed |