Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12293195 | 0.84 | HCAR3 (0.53) | RAB9ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL13658049 | 0.83 | RAB9A (0.43) | RAB9ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL14349627 | 0.83 | RAB9A (0.43) | RAB9ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL17342209 | 0.83 | RAB9A (0.43) | RAB9ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL12293177 | 0.80 | HCAR3 (0.50) | RAB9ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL13658047 | 0.80 | LMNA (0.41) | RAB9ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL12449618 | 0.80 | CYP2C19 (0.53) | RAB9ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL13658038 | 0.78 | KCNH2 (0.44) | RAB9ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL12019745 | 0.77 | HCAR3 (0.46) | RAB9ASMN1; SMN2LMNAMAPTMEN1 | |
| SCHEMBL12830407 | 0.77 | MAPT (0.47) | RAB9ASMN1; SMN2LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021254389-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2021-12-23 | — | — | WO | disclosed |