SCHEMBL24124451

SCHEMBL24124451

Cc1ccc(Oc2nc(Oc3ccc(C(N)=O)cc3)nc(Oc3ccc(C(N)=O)cc3)n2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 14/20 0.62
PARP15 Q460N3 4/20 0.62
PARP4 Q9UKK3 2/20 0.62
PARP14 Q460N5 2/20 0.62
KMT2A Q03164 2/20 0.62
ALDH1A1 P00352 1/20 0.62
PARP16 Q8N5Y8 1/20 0.62
PARP11 Q9NR21 1/20 0.62
PARP2 Q9UGN5 3/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
PARP1 P09874 1/20 0.53
CHEK2 O96017 1/20 0.52
MMP13 P45452 1/20 0.50
PARP3 Q9Y6F1 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TNKS O95271 1/20 0.49
TNKS2 Q9H2K2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22724718 1.00 PARP10 (0.62) PARP10PARP15PARP4PARP14KMT2A
SCHEMBL24124456 0.91 PARP10 (0.75) PARP10PARP15PARP4PARP14KMT2A
SCHEMBL24592196 0.89 PARP10 (0.79) PARP10PARP15PARP4PARP14KMT2A
SCHEMBL3013339 0.89 PARP10 (0.79) PARP10PARP15PARP4PARP14KMT2A
SCHEMBL4234642 0.86 PARP10 (0.68) PARP10PARP15PARP4PARP14KMT2A
SCHEMBL22724722 0.86 RAB9A (0.62) KMT2AALDH1A1MMP13NPC1RAB9A
SCHEMBL24124455 0.84 PARP10 (0.79) PARP10PARP15PARP4PARP14KMT2A
SCHEMBL22724717 0.84 PARP10 (0.79) PARP10PARP15PARP4PARP14KMT2A
SCHEMBL24124575 0.83 TDP1 (0.67) KMT2AALDH1A1CA1CA2MMP13
SCHEMBL9325864 0.82 ALDH1A1 (0.65) KMT2AALDH1A1MMP13NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF NOC2L, RIF1, NAP1L1 PARP10 348/4885PARP15 212/4885PARP4 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.