SCHEMBL24124455

SCHEMBL24124455

NC(=O)c1ccc(Oc2nc(Oc3ccccc3)nc(Oc3ccc(C(N)=O)cc3)n2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 13/20 0.79
PARP15 Q460N3 4/20 0.64
PARP14 Q460N5 2/20 0.64
ALDH1A1 P00352 2/20 0.64
KMT2A Q03164 1/20 0.64
PARP16 Q8N5Y8 1/20 0.64
PARP11 Q9NR21 1/20 0.64
PARP4 Q9UKK3 1/20 0.64
PARP2 Q9UGN5 2/20 0.59
TNKS O95271 1/20 0.59
TNKS2 Q9H2K2 1/20 0.59
POLB P06746 1/20 0.54
CYP3A4 P08684 1/20 0.54
PARP1 P09874 1/20 0.54
MAPT P10636 1/20 0.54
TSHR P16473 1/20 0.54
CYP2C19 P33261 1/20 0.54
RECQL P46063 1/20 0.54
BLM P54132 1/20 0.54
PMP22 Q01453 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22724717 1.00 PARP10 (0.79) PARP10PARP15PARP14ALDH1A1KMT2A
SCHEMBL24124456 0.92 PARP10 (0.75) PARP10PARP15PARP14ALDH1A1KMT2A
SCHEMBL24124450 0.91 PARP10 (0.66) PARP10PARP15PARP14ALDH1A1KMT2A
SCHEMBL24124449 0.91 PARP10 (0.66) PARP10PARP15PARP14ALDH1A1KMT2A
Terephthalamide SCHEMBL4205368 0.88 PARP10 (1.00) PARP10PARP15PARP14ALDH1A1KMT2A
SCHEMBL606429 0.88 PARP10 (1.00) PARP10PARP15PARP14ALDH1A1KMT2A
SCHEMBL22724757 0.87 SRD5A2 (0.67) PARP10PARP15ALDH1A1CYP3A4CYP2C19
SCHEMBL24124098 0.87 SRD5A2 (0.67) PARP10PARP15ALDH1A1CYP3A4CYP2C19
Diphenylether SCHEMBL3939335 0.86 PARP10 (0.96) PARP10PARP15PARP14ALDH1A1KMT2A
SCHEMBL24124451 0.84 PARP10 (0.62) PARP10PARP15PARP14ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF NOC2L, RIF1, NAP1L1 PARP10 348/4885PARP15 212/4885PARP14 419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.