Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 14/20 | 1.00 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.83 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.83 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.83 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.83 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.83 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.72 |
| ▸ | TNKS | O95271 | 1/20 | 0.72 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.72 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.63 |
| ▸ | PARP1 | P09874 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalamide SCHEMBL4205368 | 1.00 | PARP10 (1.00) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| Diphenylether SCHEMBL3939335 | 0.98 | PARP10 (0.96) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| Acetic Acid SCHEMBL4630327 | 0.94 | PARP10 (0.89) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| Diphenylether SCHEMBL3013964 | 0.93 | PARP10 (0.88) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| SCHEMBL3137816 | 0.91 | PARP10 (1.00) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| Fumaric Acid SCHEMBL3318252 | 0.91 | PARP10 (0.82) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| Diphenylether SCHEMBL6865503 | 0.90 | PARP10 (0.81) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| Diphenylether SCHEMBL28000843 | 0.89 | PARP10 (0.81) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| SCHEMBL24124455 | 0.88 | PARP10 (0.79) | PARP10PARP15PARP14PARP4ALDH1A1 | |
| SCHEMBL22724717 | 0.88 | PARP10 (0.79) | PARP10PARP15PARP14PARP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 712 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3037412-B1 | INDOLE AMIDE COMPOUND AS INHIBITOR OF NECROSIS | LG CHEMICAL LTD (KR) | 2020-09-30 | — | — | EP | claimed |
| CN-105658625-B | Indole amide compounds as inhibitors of cellular necrosis | 株式会社LG化学 | 2019-05-03 | — | — | CN | claimed |
| CN-109678788-A | A kind of 1,2- diaryl indoles, derivative and its synthetic method | 湘潭大学 | 2019-04-26 | — | — | CN | claimed |
| CN-109153655-A | For preventing or treating the novel N- acyl urea derivatives of cardiovascular disease and comprising its composition | 高丽大学校产学协力团 | 2019-01-04 | — | — | CN | claimed |
| CN-108997546-A | A kind of carbon containing nitrogen and the benzoxazine resin of azo structure and preparation method thereof | 西南石油大学 | 2018-12-14 | — | — | CN | claimed |
| CN-108997548-A | A kind of photolytic activity benzoxazine resin and preparation method thereof | 西南石油大学 | 2018-12-14 | — | — | CN | claimed |
| CN-108997228-A | The preparation method and application of 6- chloropyrazine -2- amides compound containing diphenyl ether base | 陈磊 | 2018-12-14 | — | — | CN | claimed |
| CN-108892646-A | Chloro- 2- pyrazinamide class compound of a kind of 6- containing diphenyl ether base and the preparation method and application thereof | 上海凯爱网络科技有限公司 | 2018-11-27 | — | — | CN | claimed |
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| CN-108003054-A | A kind of chrysanthemum amide compound containing diphenyl ether and preparation method and application | 河北大学 | 2018-05-08 | — | — | CN | claimed |
| CN-1323195-A | UV protection compositions | PROCTER & GAMBLE (US) | 2001-11-21 | — | — | CN | claimed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| CN-1310621-A | Substituted anilide compounds and methods | SMITHKLINE BEECHAM CORP (US) | 2001-08-29 | — | — | CN | claimed |
| WO-2001044179-A1 | NOVEL SUCCINATE COMPOUNDS, COMPOSITIONS AND METHODS OF USE AND PREPARATION | VERSICOR, INC. (US) | 2001-06-21 | — | — | WO | claimed |
| WO-2001009106-A1 | DIAMINO-1,2,4-TRIAZOLE-CARBOXYLIC AND DERIVATIVES AS GSK-3 INHIBITORS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-02-08 | — | — | WO | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| WO-2000006146-A9 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2000-08-03 | — | — | WO | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| CN-1049495-A | Butyro-derivative | CIBA GEIGY AG (CH) | 1991-02-27 | — | — | CN | claimed |