Terephthalamide

Terephthalamide

SCHEMBL4205368

NC(=O)c1ccc(C(N)=O)cc1.c1ccc(Oc2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 14/20 1.00
PARP15 Q460N3 4/20 0.83
PARP14 Q460N5 2/20 0.83
PARP4 Q9UKK3 2/20 0.83
ALDH1A1 P00352 1/20 0.83
KMT2A Q03164 1/20 0.83
PARP16 Q8N5Y8 1/20 0.83
PARP11 Q9NR21 1/20 0.83
PARP2 Q9UGN5 3/20 0.72
TNKS O95271 1/20 0.72
TNKS2 Q9H2K2 1/20 0.72
PARP3 Q9Y6F1 1/20 0.63
PARP1 P09874 2/20 0.62
POLB P06746 1/20 0.62
CYP3A4 P08684 1/20 0.62
MAPT P10636 1/20 0.62
TSHR P16473 1/20 0.62
CYP2C19 P33261 1/20 0.62
RECQL P46063 1/20 0.62
BLM P54132 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL606429 1.00 PARP10 (1.00) PARP10PARP15PARP14PARP4ALDH1A1
Diphenylether SCHEMBL3939335 0.98 PARP10 (0.96) PARP10PARP15PARP14PARP4ALDH1A1
Acetic Acid SCHEMBL4630327 0.94 PARP10 (0.89) PARP10PARP15PARP14PARP4ALDH1A1
Diphenylether SCHEMBL3013964 0.93 PARP10 (0.88) PARP10PARP15PARP14PARP4ALDH1A1
SCHEMBL3137816 0.91 PARP10 (1.00) PARP10PARP15PARP14PARP4ALDH1A1
Fumaric Acid SCHEMBL3318252 0.91 PARP10 (0.82) PARP10PARP15PARP14PARP4ALDH1A1
Diphenylether SCHEMBL6865503 0.90 PARP10 (0.81) PARP10PARP15PARP14PARP4ALDH1A1
Diphenylether SCHEMBL28000843 0.89 PARP10 (0.81) PARP10PARP15PARP14PARP4ALDH1A1
SCHEMBL24124455 0.88 PARP10 (0.79) PARP10PARP15PARP14PARP4ALDH1A1
SCHEMBL22724717 0.88 PARP10 (0.79) PARP10PARP15PARP14PARP4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090142567-A1 THERMALLY CONDUCTIVE ARAMID-BASED DIELECTRIC SUBSTRATES FOR PRINTED CIRCUIT BOARDS AND INTEGRATED CIRCUIT CHIP PACKAGING E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-04 US claimed
EP-0915125-B1 Laminate base material, method of preparing the same, prepreg and laminate OJI PAPER CO (JP) 2004-07-14 EP claimed
US-6261414-B1 HIGH-FREQUENCY CHARACTERISITICS, LESS WARP OF PRINTED BOARD BY LOWERING HYGROSCOPICITY; SLURRYING AND BONDING AROMATIC POLYAMIDE AND PHENOLIC RESIN FIBERS FORMING NON-WOVEN FABRIC, CURE BY COMPRESSING UNDER HEAT OJI PAPER CO., LTD. (JP) 2001-07-17 US claimed
EP-0915125-A2 Laminate base material, method of preparing the same, prepreg and laminate OJI PAPER CO., LTD. (JP) 1999-05-12 EP claimed
JP-11117184-A None JP disclosed
JP-11131385-A None JP disclosed
US-20090142567-A1 THERMALLY CONDUCTIVE ARAMID-BASED DIELECTRIC SUBSTRATES FOR PRINTED CIRCUIT BOARDS AND INTEGRATED CIRCUIT CHIP PACKAGING E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-04 US disclosed
EP-0915125-B1 Laminate base material, method of preparing the same, prepreg and laminate OJI PAPER CO (JP) 2004-07-14 EP disclosed
US-6261414-B1 HIGH-FREQUENCY CHARACTERISITICS, LESS WARP OF PRINTED BOARD BY LOWERING HYGROSCOPICITY; SLURRYING AND BONDING AROMATIC POLYAMIDE AND PHENOLIC RESIN FIBERS FORMING NON-WOVEN FABRIC, CURE BY COMPRESSING UNDER HEAT OJI PAPER CO., LTD. (JP) 2001-07-17 US disclosed
JP-2001009709-A POLISHING WORKPIECE HOLDING MEMBER SHIN KOBE ELECTRIC MACH CO LTD 2001-01-16 JP disclosed
JP-H11131385-A SUBSTRATE FOR LAMINATED PLATE, ITS PRODUCTION, PREPREG AND LAMINATED BOARD OJI PAPER CO LTD 1999-05-18 JP disclosed
EP-0915125-A2 Laminate base material, method of preparing the same, prepreg and laminate OJI PAPER CO., LTD. (JP) 1999-05-12 EP disclosed
JP-H11117184-A BASE MATERIAL FOR LAMINATE, ITS PRODUCTION, PREPREG AND LAMINATED BOARD OJI PAPER CO LTD 1999-04-27 JP disclosed