Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 2/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12411112 | 0.76 | SYK (0.50) | SYKPDK2PDK4ADORA2AADORA1 | |
| SCHEMBL14934987 | 0.74 | SYK (0.48) | SYKPDK2PDK4ADORA2AADORA1 | |
| SCHEMBL18013223 | 0.71 | HTR3E (0.47) | SYKPDK2PDK4PIM1PIM3 | |
| SCHEMBL18176130 | 0.71 | PIM1 (0.50) | SYKPDK2PDK4PIM1PIM3 | |
| SCHEMBL14890705 | 0.71 | SYK (0.44) | SYKPDK2PDK4PIM1PIM3 | |
| SCHEMBL2637996 | 0.68 | SYK (0.47) | SYKPDK2PDK4PIM1PIM3 | |
| SCHEMBL2637993 | 0.68 | SYK (0.47) | SYKPDK2PDK4PIM1PIM3 | |
| SCHEMBL2638109 | 0.68 | SYK (0.47) | SYKPDK2PDK4PIM1PIM3 | |
| SCHEMBL8326245 | 0.65 | SYK (0.48) | SYKADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL8326248 | 0.65 | SYK (0.48) | SYKADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | claimed |