Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CCL2 | P13500 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27582274 | 0.91 | DYRK1A (0.43) | DYRK1AMAOAUHRF1ALDH1A1CASP1 | |
| Hydrochloric Acid SCHEMBL28096734 | 0.89 | DYRK1A (0.42) | DYRK1AMAOAUHRF1ALDH1A1CASP1 | |
| SCHEMBL17918921 | 0.82 | UHRF1 (0.45) | DYRK1AMAOAUHRF1ALDH1A1CASP1 | |
| SCHEMBL15223391 | 0.82 | CCR1 (0.61) | DYRK1AMAOACCR1CCR5CCR8 | |
| SCHEMBL26944233 | 0.81 | UHRF1 (0.43) | DYRK1AUHRF1ALDH1A1CASP1CASP7 | |
| SCHEMBL729149 | 0.79 | MAOA (0.44) | DYRK1AMAOACCR1CCR5CCR8 | |
| SCHEMBL731492 | 0.79 | NOS3 (0.63) | DYRK1AMAOACCR1CCR5CCR8 | |
| SCHEMBL31543475 | 0.79 | MAOA (0.44) | DYRK1AMAOACCR1CCR5CCR8 | |
| SCHEMBL25308169 | 0.79 | MAOA (0.44) | DYRK1AMAOACCR1CCR5CCR8 | |
| SCHEMBL29615484 | 0.79 | NOS3 (0.63) | DYRK1AMAOACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021253098-A1 | AMIDO COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2021-12-23 | — | — | WO | disclosed |