Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.63 |
| ▸ | NOS1 | P29475 | 3/20 | 0.63 |
| ▸ | NOS2 | P35228 | 3/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 8/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731492 | 1.00 | NOS3 (0.63) | NOS3NOS1NOS2DYRK1AMAOA | |
| SCHEMBL15689737 | 0.83 | NOS3 (0.60) | NOS3NOS1NOS2DYRK1AKDM4E | |
| SCHEMBL4555865 | 0.82 | NCF1 (0.59) | NOS3NOS1NOS2DYRK1AKDM4E | |
| SCHEMBL25595272 | 0.81 | NOS3 (0.58) | NOS3NOS1NOS2DYRK1AKDM4E | |
| SCHEMBL21999454 | 0.81 | NOS3 (0.57) | NOS3NOS1NOS2DYRK1AKDM4E | |
| SCHEMBL15223391 | 0.81 | CCR1 (0.61) | NOS3NOS1NOS2DYRK1AMAOA | |
| SCHEMBL24127361 | 0.79 | DYRK1A (0.49) | NOS3NOS1NOS2DYRK1AMAOA | |
| SCHEMBL27904580 | 0.79 | NOS3 (0.55) | NOS3NOS1NOS2DYRK1AKDM4E | |
| SCHEMBL19950985 | 0.79 | NOS3 (0.55) | NOS3NOS1NOS2DYRK1AMAOA | |
| SCHEMBL25877903 | 0.79 | DYRK1A (0.49) | NOS3NOS1NOS2DYRK1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955500-A | 4- (Imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives | 默克专利股份公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-114174293-A | 4- (imidazo [1,2-a ] pyridin-3-yl) -pyrimidine derivatives | 默克专利股份公司 | 2022-03-11 | — | — | CN | disclosed |