SCHEMBL2412751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4858	0.94	TAAR1 (0.47)	TAAR1HTR2AL3MBTL1KDM4EGLA
	SCHEMBL18218371	0.89	L3MBTL1 (0.46)	TAAR1HTR2AL3MBTL1KDM4EGLA
	SCHEMBL517859	0.85	TAAR1 (0.50)	TAAR1HTR2AL3MBTL1KDM4EGLA
	SCHEMBL410976	0.83	DRD4 (0.49)	TAAR1L3MBTL1KDM4EGLAALDH1A1
	SCHEMBL31403380	0.83	TAAR1 (0.48)	TAAR1HTR2AL3MBTL1SLC6A4HMOX1
	SCHEMBL7904900	0.82	TAAR1 (0.62)	TAAR1HTR2AL3MBTL1HMOX1HSP90AA1
	SCHEMBL4443825	0.81	TAAR1 (0.46)	TAAR1HTR2AL3MBTL1HMOX1TDP1
	SCHEMBL28409389	0.81	TAAR1 (0.46)	TAAR1HTR2AL3MBTL1HMOX1TDP1
	SCHEMBL11959869	0.81	IGF1R (0.50)	TAAR1L3MBTL1TDP1ALDH1A1MAPT
	SCHEMBL15583726	0.79	TAAR1 (0.59)	TAAR1HTR2AKDM4ESLC6A4HMOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.