SCHEMBL517859

SCHEMBL517859

COCCc1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.50
HTR2A P28223 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
KDM4E B2RXH2 1/20 0.49
GLA P06280 1/20 0.49
IDO1 P14902 2/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
ALDH1A1 P00352 1/20 0.43
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAOB P27338 2/20 0.40
MAOA P21397 1/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
KMT2A Q03164 1/20 0.40
THRB P10828 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NR3C1 P04150 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26987687 0.94 TAAR1 (0.50) TAAR1HTR2AL3MBTL1KDM4EGLA
SCHEMBL8417751 0.89 TAAR1 (0.45) TAAR1HTR2AL3MBTL1KDM4EGLA
SCHEMBL1338713 0.87 NR3C1 (0.44) TAAR1L3MBTL1MAOBNR3C1ADRB2
SCHEMBL4858 0.86 TAAR1 (0.47) TAAR1HTR2AL3MBTL1KDM4EGLA
SCHEMBL21382605 0.86 L3MBTL1 (0.42) TAAR1HTR2AL3MBTL1KDM4EGLA
SCHEMBL2412751 0.85 TAAR1 (0.45) TAAR1HTR2AL3MBTL1KDM4EGLA
SCHEMBL2172552 0.83 TAAR1 (0.44) TAAR1HTR2AL3MBTL1KDM4EGLA
SCHEMBL2515837 0.80 TAAR1 (0.54) TAAR1HTR2AIDO1POLBCTDSP1
SCHEMBL12926311 0.80 MAOB (0.48) TAAR1KDM4EMAPTALDH1A1NPC1
SCHEMBL29602871 0.80 TAAR1 (0.55) TAAR1HTR2AL3MBTL1KDM4EGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071990-A1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS SemiconBio Inc. (US) 2026-03-12 US disclosed
US-12504396-B2 Polycyclic aromatic bridges for molecular electronic sensors SemiconBio (US) 2025-12-23 US disclosed
US-12435128-B2 Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 TAIHO PHARMACEUTICAL CO., LTD. (JP) 2025-10-07 US disclosed
US-20250085251-A1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS Roswell Biotechnologies, Inc. (US) 2025-03-13 US disclosed
US-20250026749-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORPORATION (US) 2025-01-23 US disclosed
US-12060349-B2 Glucosylceramide synthase inhibitors GENZYME CORPORATION (US) 2024-08-13 US disclosed
WO-2024130064-A1 SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS Karuna Therapeutics, Inc. (US) 2024-06-20 WO disclosed
EP-3953491-B1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS ROSWELL BIOTECHNOLOGIES INC (US) 2023-12-06 EP disclosed
CN-110740991-B Novel biphenyl compound or salt thereof 大鹏药品工业株式会社 2023-07-04 CN disclosed
EP-3632443-B1 ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND TAIHO PHARMACEUTICAL CO LTD (JP) 2023-06-07 EP disclosed
CN-101068797-A Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof MITSUBISHI PHARMA CORP (JP) 2007-11-07 CN disclosed
EP-1816128-A1 CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2007-08-08 EP disclosed
CN-1968954-A Thienopyridine Derivatives SANKYO CO (JP) 2007-05-23 CN disclosed
EP-1764367-A1 THIENOPYRIDINE DERIVATIVES Sankyo Company, Limited (JP) 2007-03-21 EP disclosed
EP-1140896-A1 BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 Takeda Chemical Industries, Ltd. (JP) 2001-10-10 EP disclosed
US-6235771-B1 AIDS THERPAY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-05-22 US disclosed
US-6124341-A A DRUG FOR TREATING HYPERTENSION, CONGESTIVE HEART FAILURE, RESTENOSIS FOLLOWING ARTERIAL INJURY, CEREBRAL OR MYOCARDIAL ISCHEMIA OR ATHEROSCLEROSIS; VASODILUTOR ABBOTT LABORATORIES (US) 2000-09-26 US disclosed
WO-2000037455-A1 BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-06-29 WO disclosed
EP-0991620-A1 PYRROLIDINE CARBOXYLIC ACID DERIVATIVES AS ENDOTHELIN ANTAGONISTS Abbott Laboratories (US) 2000-04-12 EP disclosed
WO-1998057933-A1 PYRROLIDINE CARBOXYLIC ACID DERIVATIVES AS ENDOTHELIN ANTAGONISTS ABBOTT LABORATORIES (US) 1998-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250085251-A1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS ALK, GJB2, ALKBH3 TAAR1 249/4885HTR2A 2908/4885L3MBTL1 3135/4885
US-12435128-B2 Method for predicting therapeutic effect of LSD1 inhibitor based on expression of INSM1 INMT, CARM1, KDM1B TAAR1 4084/4885HTR2A 1857/4885L3MBTL1 176/4885
US-12060349-B2 Glucosylceramide synthase inhibitors GBA1, GBA2, GALC TAAR1 4015/4885HTR2A 4818/4885L3MBTL1 3424/4885
US-20250026749-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GBA1, GBA2, GAA TAAR1 4106/4885HTR2A 4753/4885L3MBTL1 1688/4885
US-20260071990-A1 POLYCYCLIC AROMATIC BRIDGES FOR MOLECULAR ELECTRONIC SENSORS GJB2, STIM2, SMC3 TAAR1 1329/4885HTR2A 2083/4885L3MBTL1 1558/4885
US-12504396-B2 Polycyclic aromatic bridges for molecular electronic sensors ALK, GJB2, ALKBH3 TAAR1 249/4885HTR2A 2908/4885L3MBTL1 3135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.