Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HTR5A | P47898 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414417 | 0.93 | HPGD (0.52) | HPGDALDH1A1TSHRUSP2HTR5A | |
| SCHEMBL14015153 | 0.92 | GABRA1 (0.49) | HPGDALDH1A1TSHRUSP2HTR5A | |
| SCHEMBL2410847 | 0.92 | GABRA1 (0.52) | HPGDALDH1A1TSHRUSP2HTR5A | |
| SCHEMBL2410446 | 0.89 | RAB9A (0.51) | HPGDALDH1A1TSHRGABRA1GABRB2 | |
| SCHEMBL2416620 | 0.88 | GABRA1 (0.47) | HPGDALDH1A1TSHRUSP2HTR5A | |
| SCHEMBL2408990 | 0.87 | HPGD (0.56) | HPGDALDH1A1GABRA1GABRB2MAPT | |
| SCHEMBL2412850 | 0.85 | HPGD (0.53) | HPGDALDH1A1TSHRUSP2HTR5A | |
| SCHEMBL2413423 | 0.82 | NPC1 (0.48) | HPGDALDH1A1TSHRUSP2GABRA1 | |
| SCHEMBL2414649 | 0.82 | STAT3 (0.58) | TSHRDHFRHNF4AMCL1ACMSD | |
| SCHEMBL2414418 | 0.80 | HPGD (0.49) | HPGDALDH1A1TSHRUSP2HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |
| US-7453009-B2 | Hydroxybiphenyl carboxylic acids and derivatives, method for producing the same and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-11-18 | — | — | US | disclosed |
| US-7453009-B2 | Hydroxybiphenyl carboxylic acids and derivatives, method for producing the same and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-11-18 | — | — | US | disclosed |
| US-20080027134-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-01-31 | — | — | US | disclosed |
| US-20080027134-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027134-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | GPR119, HACL2, HCAR2 | HPGD 600/4885ALDH1A1 495/4885TSHR 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.