Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX2 | Q02962 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24129343 | 0.84 | PAX2 (0.63) | PAX2ALDH1A1LMNATSHRMEN1 | |
| SCHEMBL24129395 | 0.83 | PAX2 (0.61) | PAX2ALDH1A1LMNATSHRMEN1 | |
| SCHEMBL24129236 | 0.81 | PAX2 (0.63) | PAX2ALDH1A1LMNATSHRMEN1 | |
| SCHEMBL24129190 | 0.79 | PAX2 (0.45) | PAX2ALDH1A1LMNATSHRMEN1 | |
| SCHEMBL24129416 | 0.77 | SMN1; SMN2 (0.50) | PAX2ALDH1A1LMNATSHRMEN1 | |
| SCHEMBL25616299 | 0.76 | PAX2 (0.39) | PAX2ALDH1A1LMNATSHRMEN1 | |
| SCHEMBL25616316 | 0.76 | PAX2 (0.39) | PAX2ALDH1A1LMNATSHRMEN1 | |
| SCHEMBL8686955 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRNPSR1HSD17B10 | |
| SCHEMBL24129361 | 0.75 | SMN1; SMN2 (0.48) | PAX2ALDH1A1LMNATSHRMEN1 | |
| SCHEMBL7122700 | 0.75 | SMN1; SMN2 (0.38) | ALDH1A1LMNATSHRHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257614-A1 | HETEROCYCLIC INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2021-12-23 | — | — | WO | disclosed |