Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306833 | 0.76 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL24129095 | 0.75 | PAX2 (0.47) | SMN1; SMN2ALDH1A1HPGDKDM4EEGLN2 | |
| SCHEMBL5303365 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HPGDKDM4ELMNAMAPK1 | |
| SCHEMBL4821793 | 0.72 | TSHR (0.45) | SMN1; SMN2ALDH1A1HPGDKDM4EEGLN2 | |
| SCHEMBL8916382 | 0.70 | LMNA (0.41) | SMN1; SMN2ALDH1A1HPGDKDM4EEGLN2 | |
| SCHEMBL974960 | 0.70 | LMNA (0.36) | SMN1; SMN2ALDH1A1HPGDKDM4EEGLN2 | |
| SCHEMBL4822430 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HPGDKDM4EEGLN2 | |
| SCHEMBL8916786 | 0.70 | TSHR (0.40) | SMN1; SMN2ALDH1A1HPGDKDM4EEGLN2 | |
| SCHEMBL4821987 | 0.70 | TSHR (0.40) | SMN1; SMN2ALDH1A1HPGDKDM4EEGLN2 | |
| SCHEMBL4819802 | 0.70 | LMNA (0.36) | SMN1; SMN2ALDH1A1HPGDKDM4EEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003039259-A1 | FUNGICIDES | SYNGENTA LIMITED (GB) | 2003-05-15 | — | — | WO | disclosed |