Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20323503 | 0.82 | DRD1 (0.42) | CA2DRD1ALDH1A1HPGDMAPT | |
| SCHEMBL15485853 | 0.82 | PSIP1 (0.57) | CA2TP53DRD1MAPTPSIP1 | |
| SCHEMBL172035 | 0.78 | CA2 (0.64) | CA2TP53UCHL1KMT2AL3MBTL1 | |
| SCHEMBL23665894 | 0.77 | CA2 (0.47) | CA2KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL15177112 | 0.76 | GAA (0.54) | CA2DRD1KMT2AALDH1A1HPGD | |
| SCHEMBL678812 | 0.75 | CA2 (0.67) | CA2TP53UCHL1KMT2AL3MBTL1 | |
| SCHEMBL23554860 | 0.74 | CA2 (0.59) | CA2TP53UCHL1DRD1KMT2A | |
| SCHEMBL24899771 | 0.74 | F2 (0.44) | CA2DRD1F2 | |
| SCHEMBL25315847 | 0.74 | ENPP2 (0.60) | CA2TP53DRD1KMT2AALDH1A1 | |
| SCHEMBL15576009 | 0.74 | CA2 (0.48) | CA2DRD1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257614-A1 | HETEROCYCLIC INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2021-12-23 | — | — | WO | disclosed |