Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27108506 | 1.00 | LMNA (0.39) | LMNATDP1PLGPLAUKLKB1 | |
| SCHEMBL24130725 | 1.00 | LMNA (0.39) | LMNATDP1PLGPLAUKLKB1 | |
| SCHEMBL24130550 | 0.84 | ACACB (0.39) | LMNATDP1PLGPLAUKLKB1 | |
| SCHEMBL25650315 | 0.84 | ACACB (0.39) | LMNATDP1PLGPLAUKLKB1 | |
| SCHEMBL620977 | 0.79 | SMN1; SMN2 (0.49) | LMNATP53KMT2AACACBMEN1 | |
| SCHEMBL12462680 | 0.77 | GAA (0.41) | LMNATDP1TP53KMT2AACACB | |
| SCHEMBL12630399 | 0.74 | TP53 (0.39) | LMNATDP1PLGPLAUTP53 | |
| SCHEMBL20077541 | 0.72 | CHRNB2 (0.39) | LMNAPLGKMT2AMEN1POLB | |
| SCHEMBL10153714 | 0.72 | CHRNB2 (0.39) | LMNAPLGKMT2AMEN1POLB | |
| SCHEMBL28837098 | 0.70 | MTNR1A (0.39) | TP53KMT2AACACBPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328310-A1 | SIRNA TARGETING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 AND SIRNA CONJUGATE | Tuojie Biotech (Shanghai) Co., Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |
| EP-4194553-A1 | MODIFIED SIRNA WITH REDUCED OFF-TARGET ACTIVITY | Tuojie Biotech (Shanghai) Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| WO-2021254360-A1 | CARBOHYDRATE MOLECULAR CLUSTER AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 上海拓界生物医药科技有限公司 | 2021-12-23 | — | — | WO | disclosed |