SCHEMBL24130652

SCHEMBL24130652

CN(CC(=O)O)C(=O)[C@@H](CCCCNC(=O)OCc1ccccc1)NC(=O)OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.60
SIRT5 Q9NXA8 1/20 0.55
SIRT2 Q8IXJ6 5/20 0.54
SIRT1 Q96EB6 5/20 0.54
SIRT3 Q9NTG7 3/20 0.53
HTT P42858 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24130242 1.00 FOLH1 (0.60) FOLH1SIRT5SIRT2SIRT1SIRT3
SCHEMBL18348898 0.83 SIRT2 (0.72) FOLH1SIRT5SIRT2SIRT1SIRT3
SCHEMBL29861739 0.83 CTSL (0.66)
SCHEMBL15871405 0.83 FOLH1 (0.65) FOLH1SIRT5SIRT2SIRT1SIRT3
SCHEMBL16250362 0.83 FOLH1 (0.65) FOLH1SIRT5SIRT2SIRT1SIRT3
SCHEMBL806151 0.83 FOLH1 (0.78) FOLH1SIRT5SIRT2SIRT1
SCHEMBL4561005 0.83 FOLH1 (0.78) FOLH1SIRT5SIRT2SIRT1
SCHEMBL464715 0.83 FOLH1 (0.78) FOLH1SIRT5SIRT2SIRT1
SCHEMBL18942773 0.81 MAPT (0.64) FOLH1
SCHEMBL17020539 0.81 TGM2 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021256546-A1 METHOD FOR INDUCING ENVIRONMENTAL STRESS TOLERANCE IN PLANTS 味の素株式会社 2021-12-23 WO disclosed