Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24133248 | 0.83 | KDM4E (0.47) | LMNAALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL28685167 | 0.83 | LMNA (0.55) | LMNAALDH1A1KDM4EHTTPOLB | |
| SCHEMBL27187718 | 0.78 | ALDH1A1 (0.51) | LMNARXRARXRBRXRGALDH1A1 | |
| SCHEMBL19025114 | 0.77 | ALDH1A1 (0.50) | LMNAALDH1A1KDM4EHTTPOLB | |
| SCHEMBL27341504 | 0.75 | LMNA (0.55) | LMNAALDH1A1KDM4EHTTPOLB | |
| SCHEMBL25897124 | 0.75 | KIF11 (0.33) | KIF11 | |
| SCHEMBL9342590 | 0.74 | KIF11 (0.44) | KIF11 | |
| SCHEMBL1620757 | 0.72 | LMNA (0.56) | LMNAALDH1A1KDM4EPOLBTUBB1 | |
| SCHEMBL22836575 | 0.72 | LMNA (0.60) | LMNAALDH1A1KDM4EHTTPOLB | |
| SCHEMBL3372169 | 0.72 | ALDH1A1 (0.53) | LMNAALDH1A1KDM4EHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257834-A1 | THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. (US) | 2021-12-23 | — | — | WO | disclosed |