Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15832162 | 0.83 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2MEN1NPC1LMNA | |
| SCHEMBL13853400 | 0.73 | CHRM2 (0.57) | CHRM2KMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL2141172 | 0.72 | HDAC3 (0.32) | CYP2C9CYP2C19HDAC3HDAC1HDAC2 | |
| SCHEMBL842161 | 0.72 | CHRM2 (0.67) | CHRM2KMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL10048212 | 0.71 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2MEN1NPC1LMNA | |
| SCHEMBL17335992 | 0.71 | CYP3A4 (0.63) | KMT2ASMN1; SMN2MEN1NPC1LMNA | |
| SCHEMBL6397368 | 0.71 | CHRM2 (0.67) | CHRM2KMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL15832140 | 0.71 | POLB (0.42) | KMT2ASMN1; SMN2MEN1LMNACYP3A4 | |
| SCHEMBL631818 | 0.71 | CHRM2 (0.59) | CHRM2KMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL5939339 | 0.71 | FFAR1 (0.56) | CHRM2KMT2ASMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3929194-A1 | SUBSTITUTED NITROGEN CONTAINING COMPOUNDS | Bristol-Myers Squibb Company (US) | 2021-12-29 | — | — | EP | disclosed |