Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28571766 | 0.98 | CHRM2 (0.57) | CHRM2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL9180552 | 0.89 | LMNA (0.52) | CHRM2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL842161 | 0.87 | CHRM2 (0.67) | CHRM2KMT2AMEN1MAPTKDM4E | |
| Toluene SCHEMBL11765535 | 0.84 | MEN1 (0.54) | CHRM2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL12437138 | 0.83 | LMNA (0.65) | CHRM2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL10052932 | 0.82 | LMNA (0.64) | CHRM2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4919923 | 0.82 | CHRM2 (0.75) | CHRM2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL6397368 | 0.81 | CHRM2 (0.67) | CHRM2KMT2AMEN1MAPTKDM4E | |
| P-Xylene SCHEMBL28771255 | 0.81 | ACHE (0.53) | CHRM2MAPTKDM4EALDH1A1POLB | |
| SCHEMBL13972835 | 0.80 | CA12 (0.69) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139308-B1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2024-07-17 | — | — | EP | disclosed |
| CN-114031477-B | Method for reducing amide compounds into amine compounds by cobalt catalysis | 浙江工业大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-114031477-A | Method for reducing amide compounds into amine compounds by cobalt catalysis | 浙江工业大学 | 2022-02-11 | — | — | CN | disclosed |
| WO-2021101919-A1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-05-27 | — | — | WO | disclosed |
| US-20210054007-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2021-02-25 | — | — | US | disclosed |
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |
| WO-2020127644-A1 | BI-FUNCTIONAL NANOHYBRIDS | UNIVERSITE DE BOURGOGNE (FR) | 2020-06-25 | — | — | WO | disclosed |
| EP-3082805-B1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INST FOR DRUG DISCOVERY LLC (US) | 2020-02-05 | — | — | EP | disclosed |
| US-10093630-B2 | Pyrazole compounds and methods of making and using same | ABIDE THERAPEUTICS, INC. (US) | 2018-10-09 | — | — | US | disclosed |
| US-10030006-B2 | Coumarin based Hsp90 inhibitors with urea and ether substituents | UNIVERSITY OF KANSAS (US) | 2018-07-24 | — | — | US | disclosed |
| US-4517012-A | ANTIDOTESW | STAUFFER CHEMICAL COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| US-4415353-A | A DICHLOROACETAMIDE AS PLANT SAFENING AGENT FOR THIOCARBAMATES | STAUFFER CHEMICAL COMPANY (US) | 1983-11-15 | — | — | US | disclosed |
| US-4415352-A | N-FURYLMETHYL DICHLOROACETAMIDES AS PLANT SAFENING AGENTS FOR DITHIOCARBAMATES | STAUFFER CHEMICAL COMPANY (US) | 1983-11-15 | — | — | US | disclosed |
| US-4392884-A | CONTAINING PLANT SAFENING AGENTS | STAUFFER CHEMICAL COMPANY (US) | 1983-07-12 | — | — | US | disclosed |
| US-4341550-A | THIOLCARBAMATE WITH PLANT SAFENING AGENT | STAUFFER CHEMICAL COMPANY (US) | 1982-07-27 | — | — | US | disclosed |
| US-4276078-A | HALOGENATED AMIDE ANTIDOTES FOR THIOCARBAMYL HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1981-06-30 | — | — | US | disclosed |
| US-4269618-A | COMPRISING A THIOLCARBAMATE AND AN ANTIDOTE OF A HALOALKYLAMIDO COMPOUND; COATING CROP SEEDS; APPLYING TO THE SOIL | STAUFFER CHEMICAL COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| US-4137070-A | CONTAINING HERBICIDAL ANTIDOTE | STAUFFER CHEMICAL COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4124376-A | HALOACETANILIDE HERBICIDE AND HALO-N,N-BISALKENYLAMIDE NONPHYTOTOXIC ANTIDOTE | STAUFFER CHEMICAL COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4021224-A | THIOCARBAMATE, WEED PEST CONTROL, ANTIDOTES | STAUFFER CHEMICAL COMPANY (US) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030006-B2 | Coumarin based Hsp90 inhibitors with urea and ether substituents | HSP90B1, HSP90AA1, HSP90AB1 | CHRM2 3848/4885KMT2A 3825/4885MEN1 3514/4885 |
| US-10093630-B2 | Pyrazole compounds and methods of making and using same | ABHD6, FAAH, FAAH2 | CHRM2 4682/4885KMT2A 2932/4885MEN1 3710/4885 |
| US-20210054007-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | TACR1, TACR2, GPBAR1 | CHRM2 640/4885KMT2A 3517/4885MEN1 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.