SCHEMBL842161

SCHEMBL842161

Cc1ccc(CNCc2ccc(C)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.67
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
LMNA P02545 2/20 0.50
IDO1 P14902 1/20 0.50
ATM Q13315 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
MAPK1 P28482 1/20 0.50
CASP1 P29466 1/20 0.50
BLM P54132 1/20 0.50
PLEC Q15149 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7625869 0.90 HTT (0.63) CHRM2KMT2AMEN1ATMTHRB
SCHEMBL22882372 0.90 CHRM2 (0.57) CHRM2KMT2AMEN1LMNAIDO1
SCHEMBL12437138 0.90 LMNA (0.65) CHRM2KMT2AMEN1LMNAATM
SCHEMBL4919923 0.89 CHRM2 (0.75) CHRM2KMT2AMEN1LMNAIDO1
SCHEMBL13057539 0.88 KMT2A (0.68) CHRM2KMT2AMEN1LMNAATM
SCHEMBL7990968 0.88 ALDH1A1 (0.59) CHRM2KMT2AMEN1LMNAKDM4E
SCHEMBL18235879 0.88 CHRM2 (0.55) CHRM2KMT2AMEN1LMNAATM
SCHEMBL4913672 0.87 CHRM2 (0.79) CHRM2KMT2AMEN1CA12CA1
SCHEMBL4917450 0.87 CHRM2 (0.79) CHRM2KMT2AMEN1CA12CA1
SCHEMBL5032223 0.87 CHRM2 (0.79) CHRM2KMT2AMEN1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784180-A4 2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2009-07-22 EP claimed
EP-1784180-A2 2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-16 EP claimed
EP-1200395-B1 UREA DERIVATIVES AS INHIBITORS OF CCR-3 RECEPTOR KIRIN BREWERY (JP) 2006-03-29 EP claimed
WO-2006029115-A2 2-AMINO 1H IMIDAZO RING SYSTEMS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-03-16 WO claimed
US-6803170-B2 MIXTURE CONTAINING ACID GENERATOR SEMICONDUCTOR LEADING EDGE TECHNOLOGIES, INC. (JP) 2004-10-12 US claimed
EP-1179749-B1 Resist composition and method for manufacturing semiconductor device using the resist composition SEMICONDUCTOR LEADING EDGE TEC (JP) 2003-10-08 EP claimed
US-20020022193-A1 Resist composition and method for manufacturing semiconductor device using the resist composition SEMICONDUCTOR LEADING EDGE TECHNOLOGIES, INC. 2002-02-21 US claimed
EP-1179749-A1 Resist composition and method for manufacturing semiconductor device using the resist composition Semiconductor Leading Edge Technologies, Inc. (JP) 2002-02-13 EP claimed
US-20240059900-A1 METAL PIGMENT, APPLICATION OF METAL PIGMENT, AND METHOD FOR MANUFACTURING METAL PIGMENT ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-02-22 US disclosed
EP-4279267-A1 METAL PIGMENT, APPLICATION OF METAL PIGMENT, AND METHOD FOR MANUFACTURING METAL PIGMENT Asahi Kasei Kabushiki Kaisha (JP) 2023-11-22 EP disclosed
US-20230323135-A1 RUST PREVENTIVE COATING COMPOSITION, RUST PREVENTIVE FILM, AND ARTICLE, AND ZINC-BASED COMPOSITE PARTICLES AND COMPOSITION CONTAINING ZINC-BASED COMPOSITE PARTICLES TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2023-10-12 US disclosed
EP-4257642-A1 RUST PREVENTIVE COATING COMPOSITION, RUST PREVENTIVE FILM, AND ARTICLE, AND ZINC-BASED COMPOSITE PARTICLES AND COMPOSITION CONTAINING ZINC-BASED COMPOSITE PARTICLES Nof Metal Coatings Asia Pacific Co., Ltd. (JP) 2023-10-11 EP disclosed
CN-116648486-A Antirust coating composition, antirust coating film, article, zinc composite particles, and composition containing zinc composite particles 恩欧富涂料(亚太)株式会社 2023-08-25 CN disclosed
US-20220135517-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND FUJIFILM CORPORATION (JP) 2022-05-05 US disclosed
WO-1994017043-A1 PROCESS FOR PREPARING QUINOLINE AMINES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-08-04 WO disclosed
US-5321047-A Antidepressant JOHN WYETH & BROTHER, LIMITED (GB) 1994-06-14 US disclosed
EP-0345068-A2 Agonist of gamma-aminobutyric acid JOHN WYETH & BROTHER LIMITED (GB) 1989-12-06 EP disclosed
US-4692256-A MOLYBDENUM-AMINE COMPLEX AND SULFUR COMPOUND; OXIDATION, WEAR AND CORROSION RESISTANCE ASAHI DENKA KOGYO K.K. (JP) 1987-09-08 US disclosed
EP-0205165-A2 Molybdenum-containing lubricant composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1986-12-17 EP disclosed
US-4098705-A ADDITIVE FOR LUBRICANTS ASAHI DENKA KOGYO K.K. (JP) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135517-A1 METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND PARG, PTGIS, MT-ATP8 CHRM2 4097/4885KMT2A 3614/4885MEN1 3206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.