SCHEMBL24136102

SCHEMBL24136102

Cc1c(F)cc(I)cc1I

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.43
HDAC1 Q13547 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL752725 0.86 HDAC1 (0.39) TTRHDAC1HDAC6
SCHEMBL2261818 0.80 TTR (0.56) TTR
SCHEMBL13349219 0.79 HDAC1 (0.35) HDAC1HDAC6
SCHEMBL30294888 0.79 RAPGEF4 (0.35) HDAC1HDAC6
SCHEMBL24699771 0.79 TTR (0.32) TTRHDAC1HDAC6
SCHEMBL3458855 0.79 RAPGEF4 (0.35) HDAC1HDAC6
SCHEMBL21765278 0.75 TTR (0.40) TTRHDAC1HDAC6
SCHEMBL25188992 0.75 HDAC1 (0.33) HDAC1HDAC6
SCHEMBL21765350 0.75
SCHEMBL20783224 0.75 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209438-B2 Fluorescent methods and materials for directed biomarker signal amplification BECTON, DICKINSON AND COMPANY (US) 2021-12-28 US disclosed