Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136102 | 0.86 | TTR (0.43) | HDAC1HDAC6TTR | |
| SCHEMBL24699771 | 0.86 | TTR (0.32) | HDAC1HDAC6TTR | |
| SCHEMBL21765350 | 0.82 | — | — | |
| SCHEMBL21765278 | 0.82 | TTR (0.40) | HDAC1HDAC6TTR | |
| SCHEMBL21760181 | 0.78 | HDAC1 (0.31) | HDAC1HDAC6 | |
| SCHEMBL21756946 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL21765351 | 0.77 | TRPV4 (0.36) | TTR | |
| SCHEMBL26088361 | 0.75 | KDM4E (0.41) | HDAC1HDAC6 | |
| SCHEMBL30004335 | 0.75 | KDM4E (0.41) | HDAC1HDAC6 | |
| SCHEMBL17733622 | 0.75 | TTR (0.32) | TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042715-A1 | FLUORINATION PROCESS | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2026-02-12 | — | — | US | claimed |
| EP-4565550-A1 | FLUORINATION PROCESS | Royal College of Surgeons in Ireland (IE) | 2025-06-11 | — | — | EP | claimed |
| CN-118525019-A | Process for preparing ledipasvir | 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) | 2024-08-20 | — | — | CN | claimed |
| WO-2024110994-A1 | A PROCESS FOR THE PREPARATION OF LEDIPASVIR | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2024-05-30 | — | — | WO | claimed |
| WO-2024028729-A1 | FLUORINATION PROCESS | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2024-02-08 | — | — | WO | claimed |
| CN-112055712-A | Processes and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2020-12-08 | — | — | CN | claimed |
| US-9487470-B2 | 4-((substituted phenyl) difluoromethyl) phenoxy carboxylic acid derivative, and preparation method and uses thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2016-11-08 | — | — | US | claimed |
| US-20150119458-A1 | 4-((SUBSTITUTED PHENYL) DIFLUOROMETHYL) PHENOXY CARBOXYLIC ACID DERIVATIVE, AND PREPARATION METHOD AND USES THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2015-04-30 | — | — | US | claimed |
| EP-2842931-A1 | 4-((SUBSTITUTED PHENYL) DIFLUOROMETHYL) PHENOXY CARBOXYLIC ACID DERIVATIVE, AND PREPARATION METHOD AND USES THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2015-03-04 | — | — | EP | claimed |
| CN-116854630-B | Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections | 吉利德科学公司 | 2026-05-19 | — | — | CN | disclosed |
| US-20260042715-A1 | FLUORINATION PROCESS | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2026-02-12 | — | — | US | disclosed |
| US-20260042715-A1 | FLUORINATION PROCESS | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2026-02-12 | — | — | US | disclosed |
| EP-4565550-A1 | FLUORINATION PROCESS | Royal College of Surgeons in Ireland (IE) | 2025-06-11 | — | — | EP | disclosed |
| EP-4565550-A1 | FLUORINATION PROCESS | Royal College of Surgeons in Ireland (IE) | 2025-06-11 | — | — | EP | disclosed |
| EP-2331515-A1 | INSCETICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2011-06-15 | — | — | EP | disclosed |
| WO-2011033251-A1 | HERBICIDAL ISOXAZOLINE DERIVATIVES | SYNGENTA LIMITED (GB) | 2011-03-24 | — | — | WO | disclosed |
| WO-2010130970-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-11-18 | — | — | WO | disclosed |
| US-20100234605-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | IM&T RESEARCH, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| WO-2010020521-A1 | INSCETICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
| WO-2009076345-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | IM & T RESEARCH, INC. (US) | 2009-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119458-A1 | 4-((SUBSTITUTED PHENYL) DIFLUOROMETHYL) PHENOXY CARBOXYLIC ACID DERIVATIVE, AND PREPARATION METHOD AND USES THEREOF | PPARA, PPARG, PPARD | HDAC1 2334/4885HDAC6 1688/4885TTR 644/4885 |
| US-20260042715-A1 | FLUORINATION PROCESS | XDH, VGF, GTF2F1 | HDAC1 2274/4885HDAC6 720/4885TTR 3070/4885 |
| US-20100234605-A1 | METHODS AND COMPOSITIONS FOR PRODUCING DIFLUOROMETHYLENE-AND TRIFLUOROMETHYL-CONTAINING COMPOUNDS | FDPS, PFAS, FBL | HDAC1 3367/4885HDAC6 1040/4885TTR 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.