Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 7/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18661790 | 0.88 | SMN1; SMN2 (0.34) | FURINRENPRSS1 | |
| SCHEMBL18661754 | 0.88 | SMN1; SMN2 (0.34) | FURINRENPRSS1 | |
| SCHEMBL17448412 | 0.88 | SMN1; SMN2 (0.34) | FURINRENPRSS1 | |
| SCHEMBL20795891 | 0.88 | FURIN (0.36) | FURINREN | |
| SCHEMBL23736705 | 0.88 | FURIN (0.36) | FURINREN | |
| SCHEMBL20159819 | 0.88 | FURIN (0.36) | FURINREN | |
| SCHEMBL21788077 | 0.87 | FURIN (0.38) | FURIN | |
| SCHEMBL27352679 | 0.87 | FURIN (0.38) | FURIN | |
| SCHEMBL23393940 | 0.87 | SIRT5 (0.39) | FURIN | |
| SCHEMBL24571690 | 0.86 | FURIN (0.37) | FURINRENPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3929217-A2 | SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES | Novartis AG (CH) | 2021-12-29 | — | — | EP | disclosed |