Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22434774 | 0.84 | ACLY (0.34) | ACLY | |
| SCHEMBL24136163 | 0.80 | — | — | |
| SCHEMBL20505400 | 0.78 | HASPIN (0.33) | ACLY | |
| SCHEMBL22434775 | 0.75 | CYP19A1 (0.34) | ACLY | |
| SCHEMBL22434780 | 0.71 | CYP19A1 (0.36) | — | |
| SCHEMBL24136162 | 0.69 | CYP11B1 (0.35) | — | |
| SCHEMBL24136189 | 0.69 | MEN1 (0.35) | — | |
| SCHEMBL24136206 | 0.69 | CYP19A1 (0.35) | — | |
| SCHEMBL20505201 | 0.69 | HASPIN (0.33) | — | |
| SCHEMBL24136159 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928836-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2021-12-29 | — | — | EP | disclosed |