Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136193 | 0.83 | HRH4 (0.33) | — | |
| SCHEMBL24136184 | 0.83 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL22434866 | 0.81 | HSD11B1 (0.36) | CYP11B1CYP11B2RAPGEF4 | |
| SCHEMBL24136189 | 0.77 | MEN1 (0.35) | — | |
| SCHEMBL24136150 | 0.77 | AR (0.32) | CYP11B1CYP11B2 | |
| SCHEMBL24136159 | 0.76 | — | — | |
| SCHEMBL20505289 | 0.75 | CHEK1 (0.34) | CYP11B1CYP11B2 | |
| SCHEMBL24136225 | 0.75 | — | — | |
| SCHEMBL24136163 | 0.74 | — | — | |
| SCHEMBL24136153 | 0.74 | PDE2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928836-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2021-12-29 | — | — | EP | disclosed |