Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.37 |
| ▸ | TUBB | P07437 | 5/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22408064 | 0.84 | HPGD (0.42) | KDM4EHPGDNQO1TUBB4ATUBB | |
| SCHEMBL24136190 | 0.82 | HPGD (0.41) | KDM4EHPGDNQO1TUBB4ATUBB | |
| SCHEMBL1144591 | 0.77 | KDM4E (0.77) | KDM4EHPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL29062784 | 0.76 | KDM4E (0.57) | KDM4EHPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL8322794 | 0.76 | KDM4E (0.57) | KDM4EHPGDMAPTPOLBKMT2A | |
| SCHEMBL29153226 | 0.75 | NQO2 (0.46) | KDM4EHPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL23836105 | 0.72 | KDM4E (0.52) | KDM4EHPGDMAPTPOLBKMT2A | |
| SCHEMBL1013714 | 0.72 | NR3C1 (0.40) | KDM4EHPGDNQO1MAPTPOLB | |
| SCHEMBL24754422 | 0.71 | LMNA (0.51) | KDM4EHPGDPOLBKMT2AALDH1A1 | |
| SCHEMBL27980836 | 0.70 | MEN1 (0.53) | KDM4EHPGDMAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928836-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | Idorsia Pharmaceuticals Ltd (CH) | 2021-12-29 | — | — | EP | disclosed |