Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 15/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 15/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 13/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | LTA4H | P09960 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19513510 | 0.83 | HDAC1 (0.76) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| Scriptaid SCHEMBL780490 | 0.80 | HDAC8 (1.00) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| Scriptaid SCHEMBL29383029 | 0.80 | HDAC8 (1.00) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL7355326 | 0.80 | HEXA (0.51) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL5852563 | 0.77 | HDAC8 (0.83) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL449404 | 0.75 | HDAC6 (0.63) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL29382031 | 0.75 | ALDH1A1 (0.90) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL411511 | 0.75 | ALDH1A1 (0.90) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL8243456 | 0.74 | HDAC8 (0.65) | HDAC8HDAC3HDAC1HDAC6HDAC2 | |
| SCHEMBL452641 | 0.73 | HDAC6 (0.51) | HDAC8HDAC3HDAC1HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429603-B1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | CHILDRENS MEDICAL CENTER (US) | 2021-12-29 | — | — | EP | disclosed |