Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14703927 | 0.98 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL24171010 | 0.86 | TP53 (0.48) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL21917560 | 0.86 | TP53 (0.48) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL11990247 | 0.85 | CHKA (0.56) | ALDH1A1KDM4EMAPTL3MBTL1GAA | |
| SCHEMBL19928242 | 0.84 | MEN1 (0.55) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL21917658 | 0.84 | TP53 (0.45) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL11984298 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTL3MBTL1GAA | |
| SCHEMBL11990304 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTL3MBTL1GAA | |
| SCHEMBL26039679 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL20883730 | 0.82 | ADRB1 (0.55) | ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. | 2023-02-09 | — | — | US | disclosed |
| US-11209365-B1 | Thallium-gadolinium-chalcogenide nanodot composition | KING ABDULAZIZ UNIVERSITY (SA) | 2021-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | MMP7, MATR3, SPINT2 | ALDH1A1 3877/4885KDM4E 1948/4885MAPT 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.