SCHEMBL24136646

SCHEMBL24136646

O=C1NCCc2cc(O)c(O)cc21

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.56
PARP10 Q53GL7 11/20 0.53
PARP1 P09874 7/20 0.53
PARP11 Q9NR21 7/20 0.53
F7 P08709 1/20 0.53
F3 P13726 1/20 0.53
ACHE P22303 2/20 0.50
PDPK1 O15530 1/20 0.50
ADCY6 O43306 1/20 0.48
ADCY3 O60266 1/20 0.48
ADCY9 O60503 1/20 0.48
ADCY5 O95622 1/20 0.48
ADCY8 P40145 1/20 0.48
ADCY7 P51828 1/20 0.48
ADCY2 Q08462 1/20 0.48
ADCY1 Q08828 1/20 0.48
ADCY4 Q8NFM4 1/20 0.48
GRM5 P41594 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29600821 1.00 KDM4E (0.56) KDM4EPARP10PARP1PARP11F7
SCHEMBL10201428 0.85 KDM4E (0.50) KDM4EPARP10PARP1PARP11F7
SCHEMBL31443844 0.85 PARP10 (0.56) KDM4EPARP10PARP1PARP11F7
SCHEMBL4500561 0.85 PARP10 (0.56) KDM4EPARP10PARP1PARP11F7
SCHEMBL5807937 0.81 ACHE (0.51) KDM4EPARP10PARP1PARP11ACHE
SCHEMBL31510260 0.80 KDM4E (0.45) KDM4EPARP10PARP1PARP11F7
SCHEMBL15680247 0.79 CA12 (0.47) PARP1ACHEADCY6ADCY3ADCY9
SCHEMBL1417646 0.77 PARP10 (0.64) PARP10PARP1PARP11F7F3
SCHEMBL29438680 0.77 PARP10 (0.69) KDM4EPARP10PARP1PARP11F7
SCHEMBL246168 0.77 PARP10 (0.69) KDM4EPARP10PARP1PARP11F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4362892-B1 COMPOSITION COMPRISING AT LEAST ONE ALKYL (POLY)GLYCOSIDE, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AND AT LEAST ONE ALKALINE AGENT OREAL (FR) 2026-04-15 EP disclosed
US-12533311-B2 Method for dyeing keratin fibres starting from isatin and from powder and/or dye extract of indigo-producing plants L'OREAL (FR) 2026-01-27 US disclosed
US-20250387309-A1 METHOD FOR THE TREATMENT OF KERATIN FIBRES COMPRISING A PRETREATMENT OR POST-TREATMENT STEP OREAL (FR) 2025-12-25 US disclosed
EP-4452203-B1 PROCESS FOR DYEING KERATIN FIBRES USING A COSMETIC COMPOSITION COMPRISING PROPANE-1,3-DIOL AND A DYEING COMPOSITION OREAL (FR) 2025-12-24 EP disclosed
US-20250375366-A1 PROCESS FOR TREATING KERATIN FIBRES USING A CARNITINE SALT OR A CARNITINE DERIVATIVE OREAL (FR) 2025-12-11 US disclosed
US-12472136-B2 Composition comprising at least one alkyl (poly)glycoside, at least one fatty alcohol, at least one fatty acid, and at least one alkaline agent L'OREAL (FR) 2025-11-18 US disclosed
US-12453683-B2 Composition comprising at least nonionic surfactant, 1,3-propanediol, at least one fatty substance, at least one colouring agent L'OREAL (FR) 2025-10-28 US disclosed
US-12453686-B2 Cosmetic composition comprising at least one alkyl (poly)glycoside, N,N-dicarboxymethylglutamic acid, propane-1,3-diol, at least one fatty substance other than fatty acids, at least one dye L'OREAL (FR) 2025-10-28 US disclosed
US-20250302715-A1 COMPOSITION COMPRISING N,N-DICARBOXYMETHYLGLUTAMIC ACID, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AT LEAST ONE POLYOL, AT LEAST ONE ALKALINE AGENT AND OPTIONALLY AT LEAST ONE DYE L'OREAL (FR) 2025-10-02 US disclosed
US-20250248915-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2025-08-07 US disclosed
WO-2023275170-A1 COMPOSITION COMPRISING AT LEAST ONE ALKANOLAMINE, A (META)SILICATE, GLYCINE AND 1,3-PROPANEDIOL L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023275210-A1 COMPOSITION COMPRISING 1,3-PROPANEDIOL AND AT LEAST ONE FATTY SUBSTANCE, ONE OR MORE OXIDATION DYES L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023275209-A1 COMPOSITION COMPRISING N,N-DICARBOXYMETHYLGLUTAMIC ACID, 1,3-PROPANEDIOL, AT LEAST ONE NONIONIC SURFACTANT, AT LEAST ONE ALKALINE AGENT AND/OR AT LEAST ONE DYE L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023275207-A1 COMPOSITION COMPRISING PROPANE-1,3-DIOL, AT LEAST ONE ALKANOLAMINE, AT LEAST ONE FATTY SUBSTANCE AND OPTIONALLY AT LEAST ONE POLYOL L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023275187-A1 COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE L'OREAL (FR) 2023-01-05 WO disclosed
CN-113082300-B Antibacterial and anticoagulant coating, preparation method and application thereof 西南交通大学 2022-05-31 CN disclosed
US-20220135582-A1 NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME HANMI PHARMACEUTICAL CO., LTD. (KR) 2022-05-05 US disclosed
EP-3929199-A1 NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME Hanmi Pharmaceutical Co., Ltd. (KR) 2021-12-29 EP disclosed
CN-113423710-A Novel heterocyclic tricyclic derivative compound and use thereof 韩美药品株式会社 2021-09-21 CN disclosed
CN-113082300-A Antibacterial and anticoagulant coating, preparation method and application thereof 西南交通大学 2021-07-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375366-A1 PROCESS FOR TREATING KERATIN FIBRES USING A CARNITINE SALT OR A CARNITINE DERIVATIVE KRT18, CRAT, CKMT1A; CKMT1B KDM4E 100/4885PARP10 1508/4885PARP1 754/4885
US-20220135582-A1 NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME EZH2, EZH1, BMI1 KDM4E 67/4885PARP10 499/4885PARP1 1497/4885
US-20250387309-A1 METHOD FOR THE TREATMENT OF KERATIN FIBRES COMPRISING A PRETREATMENT OR POST-TREATMENT STEP PROC, KRT18, VCL KDM4E 1845/4885PARP10 4698/4885PARP1 2789/4885
US-20250302715-A1 COMPOSITION COMPRISING N,N-DICARBOXYMETHYLGLUTAMIC ACID, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE FATTY ACID, AT LEAST ONE POLYOL, AT LEAST ONE ALKALINE AGENT AND OPTIONALLY AT LEAST ONE DYE KRT18, DSG1, FPGS KDM4E 1180/4885PARP10 1400/4885PARP1 1116/4885
US-12533311-B2 Method for dyeing keratin fibres starting from isatin and from powder and/or dye extract of indigo-producing plants KRT18, CUTA, KRTCAP2 KDM4E 3500/4885PARP10 1829/4885PARP1 2092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.