Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 3/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24139842 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APIK3CGSLC40A1 | |
| SCHEMBL24137459 | 0.85 | SLC40A1 (0.45) | ALDH1A1MEN1KMT2APIK3CGSLC40A1 | |
| SCHEMBL24139841 | 0.84 | SLC40A1 (0.46) | ALDH1A1MEN1KMT2APIK3CGSLC40A1 | |
| SCHEMBL24139956 | 0.82 | PIK3CG (0.49) | ALDH1A1MEN1KMT2APIK3CGSLC40A1 | |
| SCHEMBL13975457 | 0.79 | ACLY (0.53) | ALDH1A1MEN1KMT2APIK3CGSLC40A1 | |
| SCHEMBL13975453 | 0.79 | SLC40A1 (0.55) | ALDH1A1MEN1KMT2APIK3CGSLC40A1 | |
| SCHEMBL24139833 | 0.75 | SLC40A1 (0.41) | ALDH1A1MEN1KMT2ASLC40A1ACLY | |
| SCHEMBL24139765 | 0.74 | SLC40A1 (0.56) | ALDH1A1MEN1KMT2APIK3CGSLC40A1 | |
| SCHEMBL13976112 | 0.74 | SLC40A1 (0.58) | ALDH1A1MEN1KMT2APIK3CGSLC40A1 | |
| SCHEMBL13975439 | 0.74 | ACLY (0.55) | ALDH1A1MEN1KMT2APIK3CGSLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710018-B1 | MACROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS | FUNDACION CENTRO NAC DE INVESTIGACIONES ONCOLOGICAS CARLOS III (ES) | 2021-12-29 | — | — | EP | disclosed |