SCHEMBL24142153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24177825	0.90	LMNA (0.57)	TDP1NPC1RAB9AAKR1B10AKR1B1
	SCHEMBL7053944	0.84	HCAR2 (0.53)	HCAR2ESR1ESR2TDP1NPC1
	SCHEMBL24142683	0.83	KMT2A (0.56)	HCAR2TDP1L3MBTL1ALDH1A1MAPK1
	SCHEMBL24142225	0.83	MEN1 (0.40)	HCAR2ESR1ESR2L3MBTL1CA1
	SCHEMBL16672605	0.82	HCAR2 (0.47)	HCAR2ESR1ESR2TDP1NPC1
	SCHEMBL24142177	0.82	THRB (0.51)	TDP1NPC1RAB9AALDH1A1HPGD
	SCHEMBL24142667	0.82	TDP1 (0.56)	ESR1ESR2TDP1NPC1RAB9A
	SCHEMBL19105206	0.81	HCAR2 (0.50)	HCAR2ESR1ESR2TDP1NPC1
	SCHEMBL13842677	0.81	HCAR2 (0.50)	HCAR2ESR1ESR2TDP1NPC1
	SCHEMBL12128696	0.81	HCAR2 (0.50)	HCAR2ESR1ESR2TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.