Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16836956 | 0.89 | LMNA (0.62) | TDP1NPC1RAB9AAKR1B10AKR1B1 | |
| SCHEMBL19105206 | 0.86 | HCAR2 (0.50) | HCAR2TDP1ESR1ESR2NPC1 | |
| SCHEMBL13842677 | 0.86 | HCAR2 (0.50) | HCAR2TDP1ESR1ESR2NPC1 | |
| SCHEMBL12128696 | 0.86 | HCAR2 (0.50) | HCAR2TDP1ESR1ESR2NPC1 | |
| SCHEMBL24142153 | 0.84 | HCAR2 (0.49) | HCAR2TDP1ESR1ESR2NPC1 | |
| SCHEMBL4622054 | 0.84 | CA1 (0.46) | ALDH1A1HPGDLMNAFFAR1 | |
| SCHEMBL19105233 | 0.83 | HCAR2 (0.47) | HCAR2TDP1ESR1ESR2NPC1 | |
| SCHEMBL16672605 | 0.83 | HCAR2 (0.47) | HCAR2TDP1ESR1ESR2NPC1 | |
| SCHEMBL2605928 | 0.82 | HCAR2 (0.46) | HCAR2TDP1ESR1ESR2NPC1 | |
| SCHEMBL290872 | 0.81 | HCAR2 (0.53) | HCAR2TDP1ESR1ESR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221208-B2 | Methods of producing an HIV maturation inhibitor | ViiV Healthcare UK (No.4) Limited (GB) | 2019-03-05 | — | — | US | disclosed |
| EP-0866798-B1 | PREPARATION OF ESTER DERIVATIVES OF STEROIDS | POPULATION COUNCIL INC (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0866798-A4 | PREPARATION OF ESTER DERIVATIVES OF STEROIDS | POPULATION COUNCIL INC (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0866798-A1 | PREPARATION OF ESTER DERIVATIVES OF STEROIDS | THE POPULATION COUNCIL, INC. (US) | 1998-09-30 | — | — | EP | disclosed |
| US-5723489-A | ADRENERGIC BLOCKING AGENTS OR STIMULANTS FOR GASTROINTESTINAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| US-5710293-A | ACYLATION OF A NORPROGESTERONE WITH ANHYDRIDE OR ACYL HALIDE, CATALYZED BY PERCHLORIC ACID | THE POPULATION COUNCIL, CENTER FOR BIOMEDICAL RESEARCH (US) | 1998-01-20 | — | — | US | disclosed |
| WO-1997013779-A1 | PREPARATION OF ESTER DERIVATIVES OF STEROIDS | THE POPULATION COUNCIL, INC. (US) | 1997-04-17 | — | — | WO | disclosed |
| US-3954888-A | Process for the preparation of 2-phenyl-ethanol | RHONE-POULENC TEXTILE (FR) | 1976-05-04 | — | — | US | disclosed |
| US-3954888-A | Process for the preparation of 2-phenyl-ethanol | RHONE-POULENC TEXTILE (FR) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10221208-B2 | Methods of producing an HIV maturation inhibitor | TMBIM6, MCL1, FURIN | HCAR2 4470/4885TDP1 3277/4885ESR1 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.