SCHEMBL24143181

SCHEMBL24143181

CC(C)(C)OC(=O)NCCCn1nnc(-c2ccc(Br)cn2)n1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CPB2 Q96IY4 1/20 0.41
▸ CA12 O43570 4/20 0.39
▸ CA1 P00915 4/20 0.39
▸ CA2 P00918 4/20 0.39
▸ CA9 Q16790 4/20 0.39
▸ MMP1 P03956 1/20 0.39
▸ MMP2 P08253 1/20 0.39
▸ MMP3 P08254 1/20 0.39
▸ MMP7 P09237 1/20 0.39
▸ MMP9 P14780 1/20 0.39
▸ MMP8 P22894 1/20 0.39
▸ MMP13 P45452 1/20 0.39
▸ STK17B O94768 1/20 0.38
▸ STK17A Q9UEE5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24143109 0.94 LTA4H (0.40) CPB2MMP1MMP2MMP3MMP7
SCHEMBL24923066 0.79 MMP1 (0.37) MMP1MMP2MMP3MMP7MMP9
SCHEMBL31370454 0.79 CPB2 (0.43) CPB2CA12CA1CA2CA9
SCHEMBL24664858 0.78 LTA4H (0.51) —
SCHEMBL25808657 0.76 CPB2 (0.40) CPB2CA12CA1CA2CA9
SCHEMBL29712156 0.74 CA1 (0.37) CPB2CA12CA1CA2CA9
SCHEMBL30694699 0.74 NAMPT (0.41) CA1CA2
SCHEMBL23840692 0.74 NAMPT (0.41) CA1CA2
SCHEMBL23952266 0.74 CA1 (0.37) CPB2CA12CA1CA2CA9
SCHEMBL24142430 0.73 LTA4H (0.46) MMP1MMP2MMP3MMP7MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348447-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2023-11-02 — — US disclosed
US-20230219941-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHODS OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2023-07-13 — — US disclosed
US-20230126415-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF AKAGERA MEDICINES, INC. (US) 2023-04-27 — — US disclosed
US-11566023-B2 Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and method of use thereof AKAGERA MEDICINES, INC. (US) 2023-01-31 — — US disclosed
US-20210403463-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF AKAGERA MEDICINES, INC. 2021-12-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210403463-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF OXA1L, THPO, TBCD CPB2 4440/4885CA12 4835/4885CA1 4867/4885
US-20230126415-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF OXA1L, THPO, TBCD CPB2 4440/4885CA12 4835/4885CA1 4867/4885
US-20230219941-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHODS OF USE THEREOF OXA1L, THPO, TBCD CPB2 4484/4885CA12 4837/4885CA1 4864/4885
US-11566023-B2 Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and method of use thereof OXA1L, THPO, TBCD CPB2 4440/4885CA12 4835/4885CA1 4867/4885
US-20230348447-A1 OXAZOLIDINONE COMPOUNDS, LIPOSOME COMPOSITIONS COMPRISING OXAZOLIDINONE COMPOUNDS AND METHOD OF USE THEREOF OXA1L, THPO, TBCD CPB2 4440/4885CA12 4835/4885CA1 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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