Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.57 |
| ▸ | HTR2A | P28223 | 7/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17676466 | 0.86 | HTR2C (0.57) | HTR2CHTR2APRMT5CYP1A2CYP2A6 | |
| SCHEMBL24109967 | 0.83 | HTR2C (0.51) | HTR2CHTR2AHTR7P2RX7PRMT5 | |
| SCHEMBL24144443 | 0.81 | HTR7 (0.63) | HTR2CHTR2AHTR7PRMT5 | |
| SCHEMBL10193356 | 0.79 | HTR2C (0.62) | HTR2CHTR2AHTR7P2RX7PRMT5 | |
| SCHEMBL18654019 | 0.79 | HTR7 (0.42) | HTR2CHTR2AHTR7GRM2AR | |
| SCHEMBL24144949 | 0.78 | HTR7 (0.53) | HTR2CHTR2AHTR7AR | |
| SCHEMBL26674340 | 0.78 | HTR7 (0.51) | HTR2CHTR2AHTR7CYP1A2 | |
| SCHEMBL12859198 | 0.78 | HTR2C (0.60) | HTR2CHTR2AHTR7P2RX7PRMT5 | |
| SCHEMBL19173629 | 0.76 | HTR2A (0.58) | HTR2CHTR2AHTR7P2RX7PRMT5 | |
| SCHEMBL21872476 | 0.76 | HTR2C (0.46) | HTR2CHTR2AHTR7P2RX7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339886-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230339886-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-10-26 | — | — | US | disclosed |
| WO-2021263278-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339886-A1 | REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS | NR1H2, NR1H3, NR1D1 | HTR2C 3626/4885HTR2A 3630/4885HTR7 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.