SCHEMBL24144

SCHEMBL24144

CC(CCO)CC1CCCC1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
CTSK P43235 8/20 0.33
CTSL P07711 5/20 0.33
CTSB P07858 5/20 0.33
CTSH P09668 3/20 0.33
GBA1 P04062 1/20 0.32
CPB2 Q96IY4 1/20 0.31
LTA4H P09960 1/20 0.31
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24199 0.98 CTSK (0.36) ALDH1A1ALOX15CTSKCTSLCTSB
SCHEMBL31676625 0.91
SCHEMBL20272927 0.85 CTSK (0.35) ALDH1A1CTSKCTSLCTSBCTSH
SCHEMBL175124 0.85 CTSK (0.35) ALDH1A1CTSKCTSLCTSBCTSH
SCHEMBL27991241 0.81 CTSK (0.37) CTSKCTSLCTSBCTSHLTA4H
SCHEMBL20030485 0.81 CTSK (0.37) CTSKCTSLCTSBCTSHLTA4H
SCHEMBL6564247 0.80 METAP1 (0.40) ALDH1A1ALOX15
SCHEMBL4652979 0.79 CTSD (0.35) ALDH1A1CTSKCTSLCTSBCTSH
SCHEMBL12631778 0.79 CTSK (0.39) CTSKCTSLCTSBCTSHLTA4H
SCHEMBL14261875 0.79 CTSK (0.39) CTSKCTSLCTSBCTSHLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2609184-B1 PERFUMERY COMPOSITIONS AND SYNTHESIS OF A ODORANT VAZE KEDAR RAMESH (IN) 2017-02-15 EP claimed
EP-2609184-A1 SYNTHESIS OF A NOVEL ODORANT Vaze, Kedar Ramesh (IN) 2013-07-03 EP claimed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US claimed
WO-2012025934-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2012-03-01 WO claimed
US-9845443-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2017-12-19 US disclosed
US-9845443-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2017-12-19 US disclosed
US-9845443-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2017-12-19 US disclosed
EP-2609184-B1 PERFUMERY COMPOSITIONS AND SYNTHESIS OF A ODORANT VAZE KEDAR RAMESH (IN) 2017-02-15 EP disclosed
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2016-01-28 US disclosed
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2016-01-28 US disclosed
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2016-01-28 US disclosed
US-9187709-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2015-11-17 US disclosed
US-9187709-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2015-11-17 US disclosed
US-9187709-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2015-11-17 US disclosed
EP-2609184-A1 SYNTHESIS OF A NOVEL ODORANT Vaze, Kedar Ramesh (IN) 2013-07-03 EP disclosed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US disclosed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US disclosed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US disclosed
WO-2012025934-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT OR10J3, OR51E2, TAS2R10 ALDH1A1 1280/4885ALOX15 1505/4885CTSK 4251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.