SCHEMBL24145085

SCHEMBL24145085

CC(=O)O[C@@H]1O[C@H](C(=O)N2CCN(C3CCCCC3)CC2)[C@@H](OC(C)O)[C@H](OC(C)=O)[C@H]1OC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 15/20 0.41
▸ KCNH2 Q12809 1/20 0.39
▸ POLB P06746 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ SIGMAR1 Q99720 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20873269 0.91 HRH3 (0.43) HRH3KCNH2POLBHSD17B10ALDH1A1
SCHEMBL24145052 0.77 TFPI2 (0.42) POLBSIGMAR1
SCHEMBL21113009 0.76 OGA (0.35) HRH3KCNH2
SCHEMBL24145051 0.76 MEN1 (0.45) ALDH1A1
SCHEMBL24145064 0.75 SMN1; SMN2 (0.47) ALDH1A1
SCHEMBL24145178 0.75 SMN1; SMN2 (0.42) POLBALDH1A1
SCHEMBL21113011 0.75 SMN1; SMN2 (0.43) SIGMAR1ALDH1A1
SCHEMBL21112937 0.74 PPP5C (0.38) HRH3HSD17B10
SCHEMBL24145067 0.73 ALDH1A1 (0.48) ALDH1A1
SCHEMBL20873258 0.73 CHRM3 (0.38) SIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210401946-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-12-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210401946-A1 CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 HRH3 3993/4885KCNH2 4649/4885POLB 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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